Translations:How to moderate a Mastodon instance/12/en

You don't need to wait for others to report harmful content, but you can actively look for it.
If you're an admin you'll get notified about everybody who signs up on your instance. Check their profile a while after they created it and you'll be able to weed out a lot of spam accounts already.
Follow the hashtags #MastoAdmin and #FediBlock to see warnings by other users about accounts and instances that might be worth blocking.